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For several decades, poly(ethylene glycol) (PEG) and monomethyl-PEG (MPEG) have been used to enhance the properties of drugs and diagnostics or to tether an affinity ligand to a reporter system. (Learn more!) BioLink's PEG-IT!™ reagents give you the ability to design the PEGylating agent most suitable for your application. BioLink now has BRANCHED PEG-IT!™ reagents.
Poly(ethylene glycol) reagents (PEGs) have the general formula X-(CH2CH2O)n-Y. For example, in PEG diols X is HO and Y is H. We have a broad spectrum of PEG-IT!™ compounds that are available in a range of molecular weights for which X and Y are, independently, a halide (Cl, Br, I), an amino or protected amino group, an activated ester, an aldehyde or protected aldehyde, a hydroxyl group, and so forth. Use our handy form to design the PEG reagent you need.
Monomethoxy poly(ethylene glycol) reagents (MPEGs) have the general formula CH3O-(CH2CH2O)n-Y. For example, in monomethylPEG, Y is OH. We have a broad spectrum of MPEG-IT!™ compounds available in a range of molecular weights for which Y is a halide (Cl, Br, I), an amino or protected amino group, an activated ester, an aldehyde or protected aldehyde, and so forth. Use our handy form to design the MPEG reagent you need. You can design your PEG-IT!™ reagent to meet your drug / peptide / protein conjugation needs. Change the end groups on our PEG-IT!™ or MPEG-IT!™ core molecules to have the molecular weight, functionality and reactivity, and degree of dispersity that is most suitable for your applications using our convenient form. |
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